Anti-CDK5 Antibody

CDK5 (Cyclin-Dependent Kinase 5) is a proline-directed serine/threonine kinase central to neuronal migration, cortical layering, and synaptic plasticity, with additional reported roles in cytoskeletal dynamics, insulin secretion, and tumor cell motility. Produced as a recombinant rabbit monoclonal reagent by Antibodies.com, this unconjugated antibody recognizes CDK5 in human, mouse, and rat samples and is validated for Western blot, immunohistochemistry, and flow cytometry workflows.

Each vial contains 100 µl of antibody formulated in TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, supporting reproducible immunostaining and immunoblotting across neuronal cell lines, primary neuron cultures, and brain tissue sections. Applications include mapping CDK5 expression during development, profiling kinase activity in neurodegenerative disease models such as Alzheimer's and Parkinson's, and interrogating non-canonical CDK5 signaling in cancer and metabolic research.

The recombinant production approach delivers lot-to-lot consistency for longitudinal studies relying on consistent antibody performance across multiple experimental cohorts.