Anti-Cdk2 (V154) Antibody

This polyclonal antibody from Antibodies.com targets Cyclin-dependent kinase 2 (Cdk2), a serine/threonine kinase that drives the G1/S phase transition of the eukaryotic cell cycle. Raised in rabbit and supplied as a 50 µl vial at 1 mg/ml, the reagent is formulated in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2 and is provided unconjugated to give researchers full flexibility over their detection chemistry. The antibody has been validated for immunohistochemistry (IHC) and is reactive with Human, Mouse, and Rat tissue samples. Cdk2 partners with cyclin E and cyclin A to phosphorylate substrates such as Rb and Cdc6, so the reagent is well suited to studies of cell proliferation, DNA replication, cell cycle arrest, and tumor biology research where altered Cdk2 activity is implicated in disease progression. Storage at 4 °C is recommended for short term use, with aliquots suitable for longer term storage at -20 °C; avoid repeated freeze-thaw cycles to preserve binding activity.