Anti-Cdk2 (V154) Antibody

Produced in rabbit as a polyclonal reagent, this unconjugated antibody targets Cyclin-dependent kinase 2 (Cdk2), a serine/threonine kinase central to G1/S cell cycle progression and frequently investigated in cancer biology research. The immunogen corresponds to a region around residue V154 of human Cdk2, supporting specific recognition of the endogenous kinase in fixed tissue sections. Supplied at 1 mg/ml in phosphate buffered saline (pH ~7.2) with 0.05% sodium azide as a 100 µL vial, the reagent is validated for immunohistochemistry (IHC) and has been demonstrated to react with Human, Mouse, and Rat samples. Researchers apply this preparation to map Cdk2 expression across tumor microenvironments, study proliferation alongside Ki-67 or PCNA, and probe cell cycle dysregulation in melanoma, breast carcinoma, and glioblastoma models. Short-term storage refrigerated; for longer intervals, aliquot and freeze to preserve activity across multiple freeze-thaw cycles. Each lot is supplied by Antibodies.com with quality control verification for IHC specificity.