Anti-CDK2 Antibody

Raised against Cyclin-Dependent Kinase 2 (CDK2), a serine/threonine kinase of approximately 34 kDa that governs the G1/S checkpoint and the onset of DNA replication in dividing cells, this unconjugated rabbit polyclonal IgG reagent is supplied by Antibodies.com as a 100 µl liquid aliquot validated for western blot and immunohistochemistry on human samples. The antibody supports studies of cell-cycle control, oncogenic transformation, and DNA-damage response, binding endogenous CDK2 in whole-cell lysates and in formalin-fixed, paraffin-embedded tissue sections to give a nuclear and cytoplasmic staining pattern consistent with the kinase's known distribution. For handling, store at -20 °C in working aliquots to limit freeze-thaw cycles and protect from light; the host species is rabbit and clonality is polyclonal, and the reagent pairs cleanly with HRP-, biotin-, or fluorophore-conjugated secondary antibodies depending on whether the downstream readout is enzyme-based or fluorescence-based.