Anti-CDK2 Antibody

This recombinant monoclonal antibody targets cyclin-dependent kinase 2 (CDK2), a serine/threonine kinase central to G1/S and S phase cell cycle progression through phosphorylation of substrates including RB1, p21, and p27 in complex with cyclin E and cyclin A. Produced in rabbit and supplied by Antibodies.com in 100 µl format, the reagent is validated for western blot, immunocytochemistry/immunofluorescence, and immunohistochemistry workflows on human, mouse, and rat samples.

The unconjugated antibody is formulated in TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, allowing storage at -20 degrees C with minimal freeze-thaw loss of activity. Researchers investigating cell cycle deregulation in breast, ovarian, and colorectal carcinoma models, as well as DNA replication and centrosome duplication mechanisms, use this reagent to assess CDK2 expression and phosphorylation status across fixed and frozen tissue sections.

Recombinant rabbit monoclonal production supports batch-to-batch consistency and defined epitope specificity. The antibody arrives in a single-use vial ready for downstream chromogenic or fluorescent labeling with a user-supplied secondary reagent, and is shipped refrigerated; aliquoting upon arrival preserves the glycerol-stabilized stock for repeated bench-top use.