Anti-CDK2 Antibody

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com targets Cyclin-Dependent Kinase 2 (CDK2), a ~33 kDa serine/threonine kinase that drives the G1-to-S transition of the eukaryotic cell cycle by phosphorylating substrates such as the retinoblastoma protein (Rb1) and the cyclin-dependent kinase inhibitors p27^Kip1 and p21^Waf1/Cip1. Supplied as a 50 µl liquid vial, the reagent has been validated for Western blot, immunocytochemistry, and immunoprecipitation across human, mouse, and rat samples, where it recognizes endogenous levels of total CDK2 protein in cell lysates and fixed cells. The antibody supports research into cell proliferation, DNA replication, and cancer biology, where aberrant CDK2 activity, deregulated G1/S checkpoint control, and altered phosphorylation of Rb1 are frequent subjects of investigation in tumour models. For best long-term performance, aliquot upon arrival, store refrigerated, and avoid repeated freeze-thaw cycles to preserve antibody activity across multiple experiments. This product is intended for research use only and is not approved for diagnostic or therapeutic applications.