Anti-CDK2 Antibody

Generated against full-length human cyclin-dependent kinase 2 and affinity purified from rabbit serum, this unconjugated IgG reagent is supplied as a 200 µl liquid stock used in western blot, immunocytochemistry, and immunoprecipitation workflows. Antibodies.com validates the polyclonal reagent on human, mouse, and rat samples, supporting comparative cell cycle and cancer signaling studies.

The 33 kDa kinase partners with cyclin E and cyclin A to drive the G1/S transition and origin firing during DNA synthesis, and laboratories tracking retinoblastoma protein phosphorylation, replication licensing, or small-molecule CDK inhibitor screening routinely deploy the antibody in synchronized HeLa, HEK293, or Jurkat lysate panels. Refrigerated storage at 4°C preserves activity across repeated freeze-thaw cycles, and the unconjugated format allows researchers to pair it with HRP, biotin, or fluorophore-labeled secondary reagents for chemiluminescent, colorimetric, or immunofluorescence readouts. Single-use aliquots of the polyclonal antibody also minimize cross-reactivity concerns by capturing multiple epitopes on the kinase and its common phosphorylated variants, and the host species compatibility extends cleanly to goat anti-rabbit detection reagents across immunohistochemistry and chromatin immunoprecipitation extensions.