Anti-CDK10 Antibody

This rabbit polyclonal primary antibody recognizes human CDK10 (Cyclin-Dependent Kinase 10), a serine/threonine kinase that governs cell cycle progression and RNA polymerase II transcription. Supplied at 100 µl per vial in unconjugated format, the reagent is validated by Antibodies.com for Western blot and immunohistochemistry workflows, supporting protein-level detection in cultured human cells and formalin-fixed tissue specimens.

CDK10 has been studied extensively in cancer biology because altered kinase activity associates with proliferative phenotypes in breast carcinoma, gastric carcinoma, and hepatocellular carcinoma models, and the target also features in research on neuronal development and ciliopathies. The polyclonal antibody format increases the probability of recognizing multiple epitopes on the CDK10 protein, which is helpful when probing post-translational modifications, splice variants, or truncated isoforms encountered across cancer cell line panels and tissue microarrays.

Standard laboratory immunoblotting and immunostaining protocols apply, with sample preparation, blocking buffers, and detection chemistry adjusted by the user to suit their specific antigen abundance and tissue type. Store the vial refrigerated for routine use; for longer-term storage, aliquot the contents and keep frozen at -20 °C, avoiding repeated freeze-thaw cycles that can compromise polyclonal antibody titer over time.