Anti-Cdk1/Cdc2 Antibody

Polyclonal antibodies raised against Cdk1 (also known as Cdc2) are widely used to interrogate cell cycle regulation in basic and translational research. This unconjugated rabbit reagent from Antibodies.com is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, and is formatted as a 100 µl vial suitable for multiple experiments.

The antibody recognizes the cyclin-dependent kinase 1 target across human, mouse, and rat samples, making it a practical tool for comparative studies in cancer biology, mitotic progression, apoptosis, and drug response work. Validated applications include western blot, immunohistochemistry, and immunofluorescence, supporting both qualitative imaging and quantitative band-based readouts in fixed and lysed specimens.

As a polyclonal reagent, it binds multiple epitopes on Cdk1/Cdc2, which can be advantageous for detecting low-abundance protein or partially degraded targets. Researchers commonly deploy this antibody to track G2/M checkpoint activity, monitor proliferative indices in tumor sections, and characterize Cdk1-dependent signaling downstream of DNA damage and therapeutic interventions.