Anti-CDK1 Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent provides robust detection of cyclin-dependent kinase 1 (CDK1), also known as CDC2, across a wide range of experimental platforms. The antibody was raised against a synthetic peptide corresponding to human CDK1 and is affinity-purified using the immunogen to ensure specificity for the endogenous total CDK1 protein. Supplied unconjugated at 1.0 mg/mL in a 50 µL volume, the product is formulated in phosphate-buffered saline at pH 7.4 (without Mg²⁺ or Ca²⁺), containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a cryoprotectant. For short-term handling it should be kept at 4 °C, while long-term storage is recommended at –20 °C; repeated freeze/thaw cycles should be avoided to preserve activity. The reagent has been validated for Western blotting (WB), immunohistochemistry (IHC), and immunocytochemistry/immunofluorescence (ICC/IF), and it shows reliable reactivity with samples derived from human, mouse, and rat tissues, making it suitable for comparative studies in cell-cycle and cancer-research workflows. Researchers commonly employ this antibody as a centrosome and mitotic-entry marker because CDK1 phosphorylation events drive the G2/M transition. Each vial ships from St. Louis, MO with a 6–9 business-day lead time, and the product is intended strictly for research use and is not validated for diagnostic applications.