Anti-CDH1 Antibody [Assigned #A5513]

An E-cadherin (CDH1) reactive reagent from Antibodies.com, supplied as an unconjugated mouse monoclonal antibody in a 100 µl vial volume and intended for immunohistochemistry on formalin-fixed paraffin-embedded tissue sections. CDH1 encodes the epithelial transmembrane glycoprotein that mediates calcium-dependent adhesion between adjacent epithelial cells, and its expression is routinely evaluated in pathology workflows to characterize epithelial differentiation and to assess the epithelial-mesenchymal transition associated with invasive carcinoma progression. Germline CDH1 alterations underlie hereditary diffuse gastric cancer and are also investigated in lobular breast carcinoma, making dependable immunostaining useful for tumor phenotyping and lineage studies. The clone, designated A5513, is a Mouse IgG preparation that recognizes human CDH1 with no conjugated reporter attached, so laboratories can pair it with their own secondary detection systems such as HRP- or polymer-based kits. The reagent is intended for research use only, and storage recommendations plus lot-specific validation data should be confirmed on the supplied product datasheet before first use.