Anti-CDCA8 Antibody

This polyclonal primary antibody from Antibodies.com targets CDCA8 (Cell Division Cycle Associated 8), also known as Borealin or Dasra-B, a core component of the chromosomal passenger complex that regulates mitotic chromosome segregation, kinetochore attachment, and cytokinesis. The reagent is raised in rabbit, supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, and is validated for western blot and immunohistochemistry workflows. It shows reactivity with human, mouse, and rat samples, which makes it practical for comparative oncology and cell-cycle studies investigating aberrant mitosis in tumor cells. Each vial contains 100 µl of working stock; aliquoting is recommended to limit freeze-thaw cycles, and the glycerol-containing buffer keeps the antibody stable during refrigerated storage. Researchers studying aurora B kinase signaling, spindle assembly checkpoint fidelity, or chromosomal passenger complex dynamics commonly use this reagent to detect endogenous CDCA8 in cell lysates and fixed tissue sections.