Anti-CDCA1 Antibody

This polyclonal antibody from Antibodies.com targets CDCA1 (Cell Division Cycle Associated 1), a kinetochore-associated protein that participates in chromosome alignment and segregation during mitosis. The reagent is raised in rabbit and supplied as an unconjugated, ready-to-use preparation in a 100 µl vial, intended for research use only and compatible with standard western blot and immunofluorescence workflows on human-derived samples.

CDCA1 functions as a core component of the NDC80 kinetochore complex, contributing to proper kinetochore–microtubule attachment and spindle assembly checkpoint signaling. Because of its role in mitotic fidelity, CDCA1 expression is frequently examined in studies of proliferating cells, tumor biology, and cell-cycle regulation across a range of human cell lines and tissue specimens.

The antibody is validated for use in WB and IF, supporting detection of the endogenous protein in cell lysates and fixed-cell preparations. Researchers commonly pair this reagent with nuclear counterstains or proliferation indicators to investigate mitotic phenotypes, aneuploidy, or checkpoint dysregulation in cancer biology and cell division research.