Anti-cdc45 Antibody

cdc45 (cell division cycle 45) operates as a core component of the CMG replicative helicase complex, which unwinds parental DNA at replication origins and supports fork progression during S phase. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the human cdc45 target and supplied in a 100 µl volume, validated for Western blot and immunofluorescence across human, mouse, and rat samples.

The reagent suits studies of DNA replication initiation, origin firing kinetics, replication stress, checkpoint signaling, and genome stability in proliferating versus quiescent cell populations. For storage, aliquot upon receipt and freeze at -20 °C; avoid repeated freeze-thaw cycles and protect from light to maintain titre across multiple blotting and staining experiments.