Anti-Cdc42EP5 Antibody

Produced by Antibodies.com, this polyclonal antiserum targets Cdc42EP5, a member of the BORG (Binder of Rho GTPases) family of Cdc42 effector proteins that modulates actin cytoskeleton remodeling downstream of Rho-family GTPase signaling. Raised in rabbit and supplied as an unconjugated reagent in a 100 µl liquid vial format, it is validated for western blot, immunohistochemistry, and ELISA workflows on human and mouse samples. Each vial contains enough volume to support multiple rounds of probing endogenous Cdc42EP5 expression in whole-cell lysates, frozen or formalin-fixed tissue sections, and recombinant protein preparations. Because Cdc42EP5 shares sequence homology with closely related BORG paralogs such as BORG1 (Cdc42EP1) and BORG2 (Cdc42EP2), the polyclonal format enables recognition of multiple epitopes, helping preserve signal when minor target variation occurs across sample types. Investigators studying cytoskeletal dynamics, septin filament organization, neuronal morphogenesis, and Rho GTPase effector biology can deploy this reagent to map Cdc42EP5 distribution and probe its interplay with Cdc42, Rac1, and related small GTPases. Short-term refrigerated storage is recommended after opening, with aliquots kept frozen to limit repeated freeze-thaw cycles and preserve antibody activity for downstream western blot and immunostaining experiments.