Anti-CDC42EP2 Antibody

This rabbit polyclonal antibody recognizes CDC42EP2 (CDC42 Effector Protein 2), a member of the BORG family of scaffold proteins that bind activated CDC42 GTPase and help coordinate actin cytoskeleton remodeling. CDC42EP2 contributes to filopodia formation, cell-shape changes, and signaling downstream of Rho-family GTPases, making it a useful reagent for studies of cell migration, membrane dynamics, and small-GTPase-regulated pathways.

Raised in rabbit and supplied as an IgG polyclonal antibody in unconjugated format, this reagent offers flexible secondary antibody pairing. The antibody reacts with both Human and Mouse targets and is validated for Western blot application, allowing detection of endogenous CDC42EP2 in cell lysates and tissue homogenates using standard chemiluminescent Western workflows. Each vial contains 100 µl of antibody, and aliquoting upon receipt is recommended to minimize freeze-thaw cycles; for short-term use, refrigeration is suitable, while long-term storage at -20°C or below helps preserve antibody activity.

From Antibodies.com, this antibody supports research use only and is intended for investigators probing CDC42EP2 expression in cancer cell lines, neuronal models, or developmental biology systems where actin cytoskeletal remodeling is of interest.