Anti-CDC37 Antibody

Raised in rabbit against the human CDC37 protein, this polyclonal reagent from Antibodies.com targets a key Hsp90 co-chaperone involved in stabilizing client protein kinases during folding and maturation. CDC37 (Cell Division Cycle 37) partners with Hsp90 to chaperone a broad subset of kinases, including CDK4, CDK6, and several receptor tyrosine kinases, making it a frequent subject in cell signaling, cancer biology, and kinase pathway research.

Validated for Western blot and immunohistochemistry on human samples, the unconjugated antibody is supplied as 100 µl of ready-to-use antiserum in a single-use vial. It performs reliably across applications that probe steady-state CDC37 expression, examine co-chaperone recruitment to kinase complexes, or map CDC37 localization in fixed tissue sections.

Researchers commonly apply this reagent to investigate Hsp90–CDC37–kinase ternary complexes, assess chaperone dependency in tumor cell lines, or profile CDC37 levels in patient-derived tissue. The polyclonal format increases the likelihood of recognizing multiple epitopes across the target, which can be helpful when probing conserved chaperone domains or comparing CDC37 expression between normal and diseased states.