Anti-Cdc34 Antibody

This polyclonal antibody targets Cdc34, an E2 ubiquitin-conjugating enzyme essential for cell cycle progression and protein degradation via the ubiquitin-proteasome pathway. Cdc34 partners with the SCF E3 ligase complex to ubiquitinate key substrates, including the cyclin-dependent kinase inhibitor p27, driving the G1 to S phase transition. Researchers studying cell division, DNA damage response, and oncogenic signaling commonly use this reagent to detect endogenous Cdc34 in human, mouse, and rat samples.

Manufactured by Antibodies.com, the product is supplied as 100 µl of unconjugated rabbit antisera and is validated for western blot and ELISA applications. Its polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which can help when probing low-abundance bands or working with denatured lysates. The unconjugated format allows flexible pairing with custom-labeled secondary detection reagents.

For short-term storage, keep the vial at 4 °C; for longer-term stability, aliquot and freeze at -20 °C, avoiding repeated freeze-thaw cycles. The reagent is intended for research use only.