Anti-Cdc34 Antibody

This unconjugated primary antibody from Antibodies.com is a rabbit polyclonal reagent raised against Cdc34, supplied as 100 µl of liquid. Cdc34 is a ubiquitin-conjugating E2 enzyme that transfers ubiquitin onto substrates including the cyclin-dependent kinase inhibitor p27 (Kip1), targeting p27 for proteasomal degradation and thereby advancing cells through the G1 to S checkpoint of the cell cycle.

Validated for Western blot and ELISA workflows, the antibody reacts with human, mouse, and rat samples, supporting investigations of cell cycle progression, ubiquitin-mediated protein turnover, and proteasome pathway biology in cancer research, neurobiology, and basic cell biology models. Because it is supplied unconjugated, the reagent can be paired with HRP, biotin, fluorophore, or bead-based detection chemistries to suit any downstream application. For best long-term use, aliquot on first thaw to limit freeze-thaw cycles and preserve polyclonal reactivity across repeated immunoblotting experiments.