Anti-Cdc25A (phospho-S76) Antibody

Cdc25A phosphatase phosphorylation at serine 76 is a key regulatory event governing G1/S cell cycle transition, DNA damage checkpoint signaling, and cyclin-dependent kinase activation. This rabbit polyclonal antibody from Antibodies.com specifically detects the phospho-S76 form, supporting research into checkpoint control, S-phase entry, and oncogenic transformation in dividing cells.

Validated for immunohistochemistry, this unconjugated antibody is supplied at 1 mg/ml in a 100 µl vial of phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2. It cross-reacts with human, mouse, and rat samples for comparative studies across model organisms. For IHC staining, dilute to working concentration, apply to formalin-fixed tissue sections, and pair with a secondary detection system of choice. Short-term storage at 4°C is acceptable; aliquot to limit freeze-thaw cycles, and protect from light to preserve phospho-specific binding activity over long-term storage at -20°C.