Anti-CDC23 Antibody

Rabbit polyclonal IgG antibody raised against CDC23, a core subunit of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase that drives mitotic progression and the metaphase-to-anaphase transition by targeting securin and cyclin B for ubiquitin-dependent proteolysis. Supplied as 100 µL of unconjugated antisera for use in western blot (WB) and immunohistochemistry (IHC) workflows on human samples, the reagent is compatible with standard immunodetection protocols and is suited to researchers studying chromosome segregation, spindle assembly checkpoint function, and cell cycle exit.

Produced in rabbit and purified as a polyclonal IgG preparation, this Antibodies.com primary antibody targets the CDC23 protein (also known as APC8), an essential component required for proper ubiquitin ligase activity of the APC/C holoenzyme. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents, and the 100 µL volume supports multiple replicate experiments.