Anti-Cdc2 Antibody

This rabbit polyclonal antibody from Antibodies.com targets Cdc2, the cyclin-dependent kinase 1 (CDK1) that drives the G1/S and G2/M transitions of the eukaryotic cell cycle. Raised in rabbit and supplied as an unconjugated reagent, it is validated for Western Blot and ELISA workflows and shows reactivity against Human, Mouse, and Rat samples, supporting comparative studies across these common model systems.

Cdc2/CDK1 is a ~34 kDa serine/threonine kinase whose activity is tightly controlled by cyclin A and cyclin B binding, phosphorylation, and association with regulatory subunits such as Cks1. Because it sits at the heart of mitotic entry, the kinase is a frequent marker in cell proliferation assays, cancer research, and studies of checkpoint signaling, where changes in expression or phosphorylation state help distinguish proliferating from quiescent populations.

The product is provided as a 100 µL liquid vial of polyclonal antiserum, unconjugated and free of preservative dyes, so it can be paired with secondary antibodies or direct detection chemistries of the user's choice. Intended for research use only, this reagent serves investigators probing cell-cycle regulation, mitotic progression, or the response of dividing cells to drug treatment in human, mouse, or rat model systems.