Anti-CDC2 (Ab-15) Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets CDC2 (also known as CDK1, Cyclin-Dependent Kinase 1), a serine/threonine kinase that drives the G2/M transition of the cell cycle. The reagent is supplied as 100 µl of antiserum and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

CDC2/CDK1 expression and post-translational modification are central to mitosis, DNA damage response, and tumor biology. Researchers apply this polyclonal reagent to detect endogenous kinase levels in cell lysates, fixed tissue sections, and cultured cells, where it supports investigations into checkpoint control, proliferation markers, and kinase regulation.

As a primary antibody supplied unconjugated in a vial, it pairs with HRP-, fluorophore-, or biotin-labeled secondary reagents, letting users tailor detection chemistry to their preferred substrate or imaging platform. Aliquot on receipt, store refrigerated for short-term use, and freeze in working aliquots; limit freeze-thaw cycles to preserve binding activity.