Anti-CDA Antibody

This rabbit polyclonal antibody from Antibodies.com targets cytidine deaminase (CDA), the pyrimidine salvage pathway enzyme that hydrolytically deaminates cytidine to uridine. CDA activity is a documented determinant of cellular sensitivity to cytidine analogues such as cytarabine (ara-C) in acute myeloid leukemia and gemcitabine in pancreatic cancer, which makes CDA a frequent subject in chemotherapy response and nucleoside drug metabolism research.

Supplied as 100 µl of unconjugated antisera, the reagent is validated for western blot (WB) and immunohistochemistry (IHC) on human samples, supporting protein-level studies in cultured cell lysates and in formalin-fixed tissue sections. The polyclonal format allows recognition of multiple epitopes on CDA, which can help when probing splice variants, truncated forms, or low-abundance targets in heterogeneous biological samples.

Laboratories working on nucleotide salvage pathways, pyrimidine catabolism, or biomarker development for nucleoside analogue therapies commonly use Anti-CDA Antibody from Antibodies.com to chart expression patterns across patient-derived specimens and matched treatment cohorts.