Anti-CD98 Antibody

The Antibodies.com rabbit polyclonal reagent targets CD98, also designated SLC3A2 or 4F2hc, a type II transmembrane glycoprotein that acts as the shared heavy chain of heterodimeric amino acid transporters (including LAT1 and xCT) and contributes to integrin-mediated adhesion signaling. Validated for Western blot and immunohistochemistry on human specimens, this unconjugated primary antibody is supplied as 100 µl of polyclonal antisera raised in rabbit. CD98 is broadly expressed on activated lymphocytes, epithelia, and many tumor cell lines, where its upregulation is tied to enhanced amino acid uptake and proliferative capacity. Investigators use this reagent to probe transporter subunit assembly, profile leukocyte activation, or survey malignancy-associated surface proteomes in cell lysates and fixed tissue sections.