Anti-CD95/FAS Antibody

The CD95/FAS receptor is a member of the tumor necrosis factor receptor superfamily and a well-characterized death receptor that initiates the extrinsic apoptosis cascade through FADD recruitment and caspase-8 activation. This unconjugated rabbit polyclonal reagent from Antibodies.com binds the CD95 antigen across human, mouse, and rat samples, supporting apoptosis research, immune regulation studies, and work on autoimmune lymphoproliferative syndrome.

Validated for western blot, immunohistochemistry, and immunofluorescence workflows, the antibody is supplied as 100 µl of a 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol. The polyclonal format recognizes several epitopes on the FAS receptor, helping track full-length and cleaved receptor forms in cell lysates and tissue sections. Investigators studying tumor immune evasion, T-cell homeostasis, or chemotherapeutic sensitization frequently use this reagent to monitor FAS expression alongside downstream caspase activation.

For long-term stability, store the vial at -20 °C and protect from light; aliquoting on first use is recommended to limit freeze-thaw cycles that can degrade polyclonal preparations.