Anti-CD8A Antibody

This rabbit polyclonal antibody from Antibodies.com targets the CD8A protein, a transmembrane glycoprotein that functions as a co-receptor for the T-cell receptor complex on cytotoxic T lymphocytes. Raised in rabbits and supplied as an unconjugated reagent at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide (approximate pH 7.2), the reagent is validated for Western blot detection of human, mouse, and rat CD8A.

CD8A, also referred to as CD8 alpha or Leu-2, belongs to the immunoglobulin superfamily and associates with major histocompatibility complex (MHC) class I molecules on antigen-presenting cells. It serves as a widely used immunological marker for cytotoxic and suppressor T-cell populations in research contexts spanning tumor immunology, transplant rejection studies, infectious disease models, and lymphocyte subset characterization.

The 100 µl format provides enough reagent for multiple immunoblotting experiments. For best results, store refrigerated and protect from light. Because the antibody is polyclonal, it recognizes several epitopes on the CD8A target, supporting robust signal development in Western blot applications across the three listed species.