Anti-CD86 Antibody

CD86 is a type I transmembrane glycoprotein belonging to the B7 family of immune co-stimulatory ligands, providing the second signal required for T-cell activation alongside CD28 interaction. This unconjugated recombinant monoclonal reagent from Antibodies.com is raised in rabbit and validated for western blot, immunocytochemistry and immunofluorescence, immunohistochemistry, and flow cytometry across human, rat, and cynomolgus monkey samples. The antibody is supplied as 50 µl of liquid formulation in TBS buffer (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative. Researchers apply it to characterize dendritic cell and B-cell maturation states, profile tumor-infiltrating leukocytes, and study antigen presentation pathways in transplant, autoimmune, and infectious disease research. Store refrigerated at 4°C; avoid repeated freeze-thaw cycles to preserve binding activity. The unconjugated format allows flexible pairing with custom fluorophore or enzyme conjugates depending on the experimental workflow.