Anti-CD68 Antibody

This Rabbit polyclonal reagent from Antibodies.com targets CD68, a lysosomal glycoprotein widely used as a marker for macrophages and monocyte-derived cells. The antibody is supplied as a 50 µl liquid formulation at 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, and was affinity-purified from rabbit antiserum by affinity-chromatography using an epitope-specific immunogen (a synthetic peptide derived from the internal region of human CD68). It is unconjugated, which makes it suitable for use with secondary-labeling systems of the researcher's choice, and its polyclonal format offers broader epitope coverage for detecting endogenous CD68 levels in biological samples. Validation data on the Antibodies.com product page list ELISA, Western blot (WB), immunocytochemistry/immunofluorescence (ICC/IF) and immunohistochemistry (IHC) as supported applications, and the antibody is reported to react with Human, Mouse and Rat samples, enabling cross-species studies of macrophage biology, inflammation and phagocytic activity. The host species is Rabbit and the clonality is Polyclonal, with no isotype explicitly stated on the supplier datasheet. Researchers handling this reagent should observe standard cold-chain precautions consistent with the glycerol/azide buffer composition, and aliquoting is recommended to limit freeze–thaw cycles. As a catalog primary antibody, it is intended for research use and is well matched to labs investigating monocyte/macrophage markers, tissue-resident immune cells, atherosclerotic plaque macrophages, tumor-associated macrophage populations, and general studies of the lysosomal/endosomal system where CD68 serves as a robust phenotypic indicator.