Anti-CD66e Antibody

CD66e, also designated CEACAM5 or CEA, is a GPI-anchored cell-surface glycoprotein of the carcinoembryonic antigen immunoglobulin superfamily. It is widely studied as a tumor-associated antigen in colorectal, pancreatic, gastric, and other epithelial malignancies, where altered surface expression and shedding into circulation are linked to disease progression. This unconjugated rabbit polyclonal reagent from Antibodies.com targets the human CD66e protein and is validated for western blot and ELISA workflows.

Provided as a 50 µL liquid aliquot, the antibody recognizes epitopes across the extracellular Ig-like domain region of CD66e, supporting detection of both recombinant and natively expressed CEACAM5 in cell lysates, tissue extracts, and conditioned media. The polyclonal format allows multi-epitope recognition, which is useful when surveying expression patterns in patient-derived samples or engineered cell lines. Because the reagent is supplied unconjugated, investigators can pair it with HRP, biotin, fluorophore, or bead-based secondary systems to match their preferred detection chemistry.

For routine handling, refrigerate the vial, protect it from light, and aliquot upon first use to limit freeze-thaw cycles. The product is intended for research use only and is not approved for diagnostic or therapeutic applications.