Anti-CD59 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets CD59, a GPI-anchored membrane glycoprotein that regulates the terminal complement pathway by inhibiting assembly of the membrane attack complex on host cell surfaces. Raised in rabbit and supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is validated for Western blot and immunohistochemistry workflows, with reactivity established against human CD59. The 100 µl vial suits multiple immunostaining or blotting experiments, and the glycerol-containing buffer permits storage at -20 °C with minimal freeze-thaw loss. Researchers studying paroxysmal nocturnal hemoglobinuria, complement-mediated cell lysis, or GPI-anchor biosynthesis apply this reagent to characterize CD59 surface expression on erythrocytes, leukocytes, and vascular endothelium in tissue sections and cell lysates.