Anti-CD58 Antibody

Produced as a Rabbit polyclonal reagent targeting the CD58 cell surface glycoprotein, this unconjugated primary antibody from Antibodies.com supports Western blot and ELISA workflows on human samples. CD58, also known as LFA-3, is an immunoglobulin-superfamily adhesion molecule that engages CD2 on T cells and natural killer cells, contributing to immunological synapse formation and lymphocyte activation.

The antibody is supplied as 100 µl of liquid, and its polyclonal nature means it recognizes multiple epitopes on the human CD58 protein, increasing tolerance for minor sample variation. Researchers studying immune cell-cell adhesion, antigen presentation, costimulatory signaling, and tumor-immune interactions commonly use anti-CD58 reagents to characterize expression on lymphocytes, epithelial cells, and antigen-presenting cells.

The unconjugated format allows researchers to couple the antibody to their preferred label such as HRP, biotin, or a fluorophore depending on assay design. Reactivity has been validated against human targets, making this reagent appropriate for studies of hematopoietic and epithelial systems where CD58 mediates contact-dependent immune signaling.