Anti-CD58 Antibody

Raised in rabbits, this unconjugated polyclonal antibody from Antibodies.com selectively recognizes human CD58, the immunoglobulin-superfamily adhesion molecule also called LFA-3 that engages CD2 on T lymphocytes during immune synapse assembly and target cell conjugation. Each vial contains 100 µl of affinity-purified reagent, validated for Western blot analysis of cell lysates and immunohistochemistry on frozen sections and formalin-fixed paraffin-embedded tissue. Investigators in tumor immunology, transplant rejection research, and inflammation studies apply the antibody to profile CD58 expression in lymphoma cell lines, activated lymphocyte cultures, vascular endothelium, and epithelial barriers where LFA-3-mediated co-stimulation modulates cytotoxic T-cell engagement.