Anti-CD58 Antibody

This rabbit polyclonal antibody targets human and mouse CD58 (also known as LFA-3), a 45-65 kDa cell-surface glycoprotein of the immunoglobulin superfamily that mediates adhesion between antigen-presenting cells and T lymphocytes through binding to CD2. The reagent, supplied by Antibodies.com at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol for cryoprotection, is shipped as 100 µl aliquots ready for direct dilution into standard immunoblotting and immunohistochemistry workflows.

Validated for Western blot on human and mouse samples and for immunohistochemistry on formalin-fixed tissue sections, the antibody detects endogenous CD58 expressed on B lymphocytes, T cells, monocytes, and epithelial populations. Researchers studying T cell activation, immune synapse formation, and costimulatory signaling will find this polyclonal reagent useful for probing membrane fractions and paraffin-embedded sections. The unconjugated format allows flexible pairing with custom fluorophore or enzyme conjugations to match a chosen detection chemistry.

Storage recommendations: keep the vial refrigerated at 4°C in its existing glycerol/azide buffer to preserve activity across repeated use. For long-term stability, aliquot to limit freeze-thaw cycles. Intended for research use only.