Anti-CD55 Antibody

CD55, also known as Decay Accelerating Factor (DAF), is a key regulator of the complement cascade that protects host cells from autologous complement-mediated lysis. Produced by Antibodies.com, this rabbit polyclonal antibody specifically targets the human CD55 protein, a GPI-anchored cell surface glycoprotein expressed across many tissues and blood cells. The reagent is supplied as 100 µl of unconjugated antisera and is validated for Western blot and ELISA workflows, supporting studies of complement regulation, innate immune signaling, and cell surface marker profiling.

Investigators apply anti-CD55 antibodies to research on paroxysmal nocturnal hemoglobinuria, where deficient CD55 expression leaves erythrocytes vulnerable to complement attack, and to tumor immunology studies that probe how malignant cells exploit complement regulators to evade immune surveillance. The polyclonal format provides multi-epitope recognition, useful for detecting denatured CD55 on western blot membranes or capturing the native protein in ELISA. Aliquot upon receipt and store refrigerated to preserve antibody activity across multiple experiments.