Anti-CD48 Antibody

Rabbit polyclonal antibodies raised against CD48 enable specific detection of this glycosylphosphatidylinositol-anchored surface protein in human and mouse samples. CD48, also termed SLAMF2 or BCM1, belongs to the immunoglobulin superfamily and participates in immune cell adhesion and activation signaling through interactions with CD2 and CD244 on neighboring lymphocytes. The unconjugated reagent is supplied as 100 µl of polyclonal antiserum and is validated for Western Blot and Immunohistochemistry workflows on human and mouse tissue specimens. Researchers commonly apply this antibody to probe lymphocyte surface expression, dissect NK cell and T-cell activation pathways, or examine CD48 distribution across hematopoietic lineages in lymphoid organs. The reagent, distributed by Antibodies.com, supports immunoblotting of whole-cell lysates as well as fixed-section immunohistochemistry, making it useful for basic immunology, transplant rejection studies, and hematologic oncology research where altered CD48 expression has been reported.