Anti-CD44 antigen isoform 4 Antibody

This unconjugated polyclonal primary antibody from Antibodies.com is raised in rabbit against the CD44 antigen isoform 4 variant, recognizing the human splice isoform that includes the variant exon v4. Supplied as 100 µl, the reagent supports Western blot, immunohistochemistry, and immunofluorescence workflows on human tissue and cell samples, enabling researchers to distinguish the v4-containing isoform from standard CD44 (CD44s) and other alternatively spliced variants. Common research applications include profiling isoform expression in epithelial cancers, investigating hyaluronan-mediated cell adhesion, and tracking changes in CD44v4 levels during tumor progression and metastatic spread. Polyclonal reactivity provides broader epitope coverage across the CD44 extracellular domain, which helps when probing the variant-specific insertion under variable fixation or antigen retrieval conditions during IHC staining.