Anti-CD40LG Antibody

CD40LG (also known as CD154 or TNFSF5) is the TNF-family costimulatory ligand that engages CD40 on B lymphocytes, dendritic cells, and macrophages during T-helper cell contact. This unconjugated rabbit polyclonal antibody from Antibodies.com binds the human CD40LG target and is validated for Western blot and immunofluorescence workflows, supporting research on T-B cell cognate interaction, germinal center formation, class-switch recombination, and the molecular basis of X-linked Hyper-IgM syndrome. The reagent is affinity-purified from rabbit host serum, supplied as a 100 µl liquid vial aliquot, and shipped unconjugated so it can be paired with a secondary detection reagent of the user's choice. For long-term stability, store frozen in working aliquots, limit freeze-thaw cycles, and protect from light. Reactivity is human-specific; clonality is polyclonal.