Anti-CD40 Ligand Antibody

This rabbit polyclonal antibody from Antibodies.com specifically targets CD40 Ligand (also known as CD154 or TNFSF5), a type II transmembrane costimulatory protein expressed predominantly on activated CD4+ T cells and platelets. The reagent is supplied as a 100 µl vial at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, and is unconjugated to permit flexible secondary detection in custom protocols. Validated applications include Western blot detection of endogenous CD40 Ligand in human, mouse, and rat samples, supporting research into T cell–B cell costimulatory signaling, germinal center formation, and immunoglobulin class-switch recombination. The polyclonal host configuration yields recognition of multiple epitopes across the target, useful for tracking full-length and processed forms under denaturing gel conditions. Researchers commonly aliquot the solution upon receipt and store at -20°C to limit freeze-thaw cycles, preserving antibody activity across multiple experiments.