Anti-CD40 Antibody (Biotin) [5C3]

The Anti-CD40 Antibody (Biotin) [5C3] from Antibodies.com is a mouse monoclonal antibody conjugated to biotin, recognizing the human CD40 antigen. CD40 is a 48 kDa type I transmembrane glycoprotein belonging to the TNF receptor superfamily, predominantly expressed on B lymphocytes, dendritic cells, macrophages, and other antigen-presenting cells. It mediates T cell-dependent B cell activation, immunoglobulin class switching, and germinal center formation, making it a key marker in immunology and vaccine research.

This biotinylated 5C3 clone is supplied as 50 µg in liquid format within a vial, with an IgG1 isotype. It is validated for western blot, flow cytometry, and immunohistochemistry workflows on human specimens. The biotin conjugation supports detection through streptavidin reporters, allowing signal amplification or use in multiplex panels. Store refrigerated and protect from light; avoid repeated freeze-thaw cycles. The antibody is reactive against human CD40 with no significant cross-reactivity reported for rodent species under standard assay conditions. For research use only.