Anti-CD37 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets CD37, a tetraspanin-family surface protein expressed predominantly on B lymphocytes. As a member of the transmembrane 4 superfamily, CD37 participates in B-cell receptor signaling, survival, and proliferation pathways, making it a marker of interest in studies of lymphoid biology and B-cell malignancies such as chronic lymphocytic leukemia and non-Hodgkin lymphoma.

The reagent is supplied as 100 µl of liquid stock for western blot and ELISA workflows. Raised in rabbit and purified as a polyclonal reagent, it binds the human CD37 antigen and is unconjugated for direct detection with secondary reporters such as HRP or fluorophore conjugates. For handling, the antibody should be stored refrigerated and protected from repeated freeze-thaw cycles; aliquoting upon first use preserves titer for long-term studies.

Researchers working on B-cell phenotyping, lymphoma cell-line characterization, or immunoglobulin heavy-chain complex analysis can use the reagent with whole-cell lysates to follow CD37 expression changes under different activation or treatment conditions.