Anti-CD34 Antibody [Assigned #A10796]

CD34 is a 110 kDa type I transmembrane sialomucin glycoprotein expressed on hematopoietic stem and progenitor cells and on vascular endothelium. This unconjugated rabbit monoclonal IgG antibody recognizes a conserved epitope on CD34, enabling detection across human, mouse, rat, and canine samples in translational and preclinical research workflows.

Validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation, the reagent supports studies of bone marrow and cord blood progenitor populations, tumor angiogenesis, vascular injury models, and characterization of endothelial precursors. Reactivity spanning four species makes it a practical single-lot option for comparative work in murine disease models and canine studies alongside human tissue cohorts.

The antibody is supplied at 100 µL as an unconjugated preparation, leaving downstream labeling open to fluorophores, biotin, or enzymes depending on the assay panel. Brief centrifugation before opening recovers full volume; storage refrigerated in working aliquots helps preserve epitope recognition through limited freeze-thaw cycles.

Typical applications include resolving capillary networks in tissue sections, isolating CD34-enriched cell fractions from lysates, and tracking transgene-driven expression in hematopoietic differentiation protocols. Each preparation is quality controlled at Antibodies.com to deliver consistent staining in vascular and hematopoietic marker panels.