Anti-CD33 Antibody

Rabbit polyclonal reagent targeting the CD33 transmembrane glycoprotein (Siglec-3), a 67 kDa sialic-acid-binding lectin expressed on myeloid progenitors, monocytes, and macrophages. Raised in rabbit and supplied unconjugated in a 100 µl vial, the antibody is validated for Western blot and ELISA workflows against human samples. CD33 is widely used as a surface marker in acute myeloid leukemia (AML) research and as a therapeutic target, most notably for antibody-drug conjugates such as gemtuzumab ozogamicin, making reliable polyclonal detection useful for studying expression patterns and downstream signaling in leukemic cell lines and primary hematopoietic material. The polyclonal format allows recognition of multiple epitopes on the extracellular Ig-like domain, supporting immunoblotting of full-length CD33 and related isoforms. Antibodies.com provides this reagent for laboratories investigating hematopoiesis, myeloid differentiation, and immunophenotyping in translational oncology and immunology projects.