Anti-CD31/PECAM-1 Antibody

This Mouse monoclonal antibody targets CD31 (PECAM-1), a transmembrane glycoprotein concentrated at endothelial cell junctions and routinely used as a marker of vascular endothelium in angiogenesis and vascular biology studies. Manufactured by Antibodies.com, the reagent is supplied as a 50 µl aliquot of purified mouse monoclonal antibody in PBS (pH 7.4) with 0.02% sodium azide, 0.1 mg/ml BSA, and 50% glycerol for shelf stability. Validated for western blot on human samples, it is provided unconjugated so it can be paired with HRP- or fluorophore-conjugated secondary reagents for chemiluminescent or immunofluorescent detection. Investigators working on tumor vascularization, endothelial barrier function, inflammatory cell recruitment, and leukocyte transmigration rely on this target to assess vessel density and endothelial integrity in cultured cell and tissue lysate preparations.