Anti-CD300c Antibody

The Antibodies.com polyclonal reagent targets CD300c, a type I transmembrane glycoprotein belonging to the CD300 immunoreceptor family. In human tissue, the molecule is expressed across the myeloid lineage, including monocytes, macrophages, neutrophils, and select dendritic cell subsets, where its surface levels shift with cellular activation and differentiation. Raised in rabbit and supplied as an unconjugated IgG preparation in a 100 µl vial, the antibody is validated for Western blot and ELISA workflows on human samples.

CD300c, also referenced by the alias CMRF35A, carries a single extracellular Ig-like V-type domain paired with a short cytoplasmic tail that lacks classical ITIM motifs yet modulates intracellular signaling through associated adaptor proteins. Because the receptor sits at the interface of activating and inhibitory pathways, the antibody is frequently used to characterize myeloid populations in immunological research, dissect innate immune regulation, and probe ligand binding within the broader CD300 receptor network.

Each vial ships with handling and storage guidance intended to preserve reagent performance across repeated immunoblotting and plate-based detection experiments, supporting reproducible results in studies of human leukocyte biology.