Anti-CD3-δ Antibody

The CD3-delta subunit forms part of the invariant signalling module of the T-cell receptor complex, partnering with CD3-epsilon, CD3-gamma, and the zeta chain to transduce activation signals following antigen recognition on thymocytes and mature T lymphocytes. This Antibodies.com reagent is a rabbit polyclonal antibody raised against the human CD3-delta protein and supplied as an unconjugated 100 µl liquid aliquot.

The antibody is validated for Western blot detection of endogenous CD3-delta expression in human T-cell preparations and is also applied in ELISA workflows where researchers monitor CD3-delta abundance in immunoprecipitated TCR complexes or whole-cell lysates. Because the reagent is unconjugated, laboratories can pair it with HRP, biotin, or fluorophore secondary detection systems according to the experimental design.

The polyclonal format recognises multiple epitopes across CD3-delta, which is helpful when comparing expression across T-cell developmental stages. The product is intended for research use only and works with cell culture samples, primary human T-cell isolates, and established human T-cell lines. The vial should be kept refrigerated and aliquoted upon receipt so that working portions remain free from repeated freeze-thaw cycles.