Anti-CD2AP Antibody

CD2AP (CD2-associated protein) is a multifunctional scaffolding adaptor best known for linking the T-cell adhesion receptor CD2 to the actin cytoskeleton and for maintaining the slit-diaphragm architecture of glomerular podocytes.

This unconjugated rabbit polyclonal reagent is raised against the human CD2AP sequence and is validated for Western blot and immunohistochemistry workflows. The antibody ships as 100 µL of liquid stock in a single vial, typically sufficient for multiple IHC staining runs and dozens of mini-gel blots once diluted into blocking buffer at 1:500 to 1:2000.

Common research applications include:

• Mapping CD2AP distribution in human renal biopsy sections
• Profiling CD2AP expression changes in models of focal segmental glomerulosclerosis
• Tracking CD2AP recruitment to the immune synapse in activated T lymphocytes
• Validating CD2AP knockdown or overexpression by Western blot

For long-term storage, keep frozen aliquots at -20 °C, limit freeze-thaw cycles, and protect from light. For research use only. Antibodies.com supplies this reagent within its Primary Antibodies catalog.