Anti-CD274 Antibody

Raised in rabbit and supplied by Antibodies.com as an unconjugated polyclonal reagent, this 100 µl antibody recognizes CD274 (PD-L1), a type-I transmembrane glycoprotein and key immune-checkpoint ligand. It is reactive with human samples and supports Western blot and immunohistochemistry workflows, making it a useful tool for studies of tumor immune evasion, checkpoint blockade research, and characterization of PD-L1 expression in tissue sections and cell lysates.

The reagent is supplied in a liquid format suitable for direct dilution into standard assay buffers. Researchers commonly apply it to formalin-fixed paraffin-embedded sections for IHC-based profiling of PD-L1 status across tumor types, and to whole-cell extracts for WB detection of endogenous PD-L1 levels, which often correlate with IFN-γ signaling and adaptive immune resistance mechanisms.