Anti-CD253 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets CD253, the TNF-related apoptosis-inducing ligand (TRAIL, also designated TNFSF10), and is validated for Western blot and immunofluorescence on human specimens. CD253 is a type II transmembrane cytokine that drives caspase-mediated apoptosis through the death receptors DR4 and DR5, and researchers working on tumour cell susceptibility to extrinsic apoptosis, immune-mediated cytotoxicity, or cytokine signalling in inflammatory and infectious disease contexts routinely profile this ligand at the protein level.

The unconjugated 100 µL format gives laboratories freedom to pair the reagent with their own enzyme- or fluorophore-conjugated secondary antibodies for chemiluminescent membrane readouts, fluorescent immunostaining, or other downstream detection chemistries. The polyclonal nature of the reagent offers multi-epitope recognition of human CD253, helping capture both full-length and processed forms of the ligand where expression is low or cleavage events are biologically relevant. For research use only.