Anti-CD244 Antibody

This unconjugated rabbit polyclonal reagent targets CD244, a SLAM-family receptor expressed on natural killer cells, CD8+ T cells, gamma-delta T cells, and basophils, where it modulates cytotoxic activity through its ligand CD48.

Antibodies.com supplies it as 100 µl of a 1 mg/ml stock in PBS with 0.1% sodium azide and 50% glycerol, suitable for western blot and immunohistochemistry on human and mouse tissue. The polyclonal host response increases the chance of detecting multiple epitopes on the target, which is helpful when probing activation states of NK and effector T cells in tumor immunology, viral-infection models, and autoimmune-tissue studies.

The high glycerol content allows the stock to remain liquid at -20°C, so the vial can be moved directly into a freezer without a separate cryoprotectant step; aliquot on first use to avoid repeated freeze-thaw cycles of the working stock. Each lot is validated for the listed applications, and the unconjugated format lets researchers pair the antibody with HRP, biotin, or fluorophore conjugates of their choice depending on detection chemistry.